Research Publication of Syed Salahuddin

Research Publication Details

• Khan SA, Ullah Q, Syed Salahuddin, Alimuddin, Almalki ASA, Kumar S, Obaid RJ, Alsharif MA, Alfaifi SY, Parveen H, Microwave assisted one-pot synthesis, photophysical and physicochemical studies of novel biologically active heterocyclic Donor (D)-π-Acceptor (A) chromophore..Bioorg Chem. 2021 Jul;112:104964. 
• Aillaud C, Bosc C, Peris L, Bosson A, Heemeryck P, Van Dijk J, Le Friec J, Boulan B, Vossier F, Sanman LE, Salahuddin Syed, Amara N, Couté Y, Lafanechère L, Denarier E, Delphin C, Pelletier L, Humbert S, Bogyo M, Andrieux A, Rogowski K, Moutin MJ. Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. Science. 2017 Dec 15;358(6369):1448-1453.

• Verdoes, M.; Bender, K.O.; Segal, E.; van der Linden, W. A.; Salahuddin, S.; Nimali P. Withana, N. P.; Sanman, L.E.; and Bogyo, M. An improved quenched fluorescent probe for imaging of cysteine cathepsin activity. J. Am. Chem. Soc. 2013. 135, 14726.
• Morell, M.; Nguyen Duc, T.; Willis, A. L.; Salahuddin, S.; Lee, J.; Deu, E.; Deng, Y.; Xiao, J.; Turk, B. E.; Jessen, J. R.; Weiss, S. J.; Bogyo, M. Coupling protein engineering with probe design to inhibit and image matrix metalloproteinases with controlled specificity. J. Am. Chem. Soc. 2013. 135, 9139.
• Edgington LE., Verdoes M., Ortega A., Lee J., Salahuddin, S., Bachmann M., Blum G., Bogyo.Functional imaging of legumain in cancer using a quenched activity-based probe. J Am Chem Soc. 2013 135(1):174-82.

• G., Blum G., Verdoes M., Liu H, Syed Salahuddin., Edgington LE., Gheysens O., Miao Z., Jiang H., Gambhir SS., Bogyo M., Cheng Z. Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe. PLoS One.2011; 6(11):e28029.
• Maillard, N., Babiak, P., Salahuddin, S.,Biswas, R., Mandrich, L., Manco, G., Reymond, J.-L. Fivesubstrate cocktail as a sensor array for measuring enzyme activity fingerprints of Lipases and Esterases. Anal Chem. 2011. 15;83(4):1437-42.
•  Zhang, H., Salahuddin, S.,Barbas III, C.F. Highly enantio- and diastereoselective Mannich reactions of Glycine Schiff bases with in situ generated N-Boc-imines catalyzed by a cinchona alkaloid thiourea. Organic Letters.2010. 12: 708-711.
•  Bui, T., Salahuddin, S.,Barbas, III, F.C. Thiourea-catalyzed highly enantio- and diastereoselective additions of oxindoles to nitroolefins: Application to the formal synthesis of (+)-physostigmine. J. Am. Chem. Soc. 2009. 131: 8758-8759.

• Gavrilyuk, J. L., Wuellner, U., Salahuddin, S., Goswani, R.K., Sinha, S.C., Barbas, III, F.C. Efficient chemical approaches to bispecific antibodies and antibodies of high valency. Bioorg Med ChemLett.2009. 19: 3716-3720.

• Nguyen, K.T., Luethi, E., Salahuddin, S., Urwyler, S., Bertrand, S., Bertrand, D., Reymond, J.-L. 3- (Aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitors from the Chemical Universe Database GDB. Bioorg Med ChemLett2009. 19: 3832-3835.

• Nguyen, K.T., Salahuddin, S., Urwyler, S., Bertrand, S., Bertrand, D., Reymond, J.-L. Discovery of NMDA glycine site inhibitors from the Chemical Universe Database GDB.Chem Med Chem2008. 3: 1520 -1524.
• Salahuddin, S.,Renaudet, O., Reymond, J.-L., Aldehyde detection by chromogenic/fluorogenicoxime bond fragmentation. Org. Biomol. Chem.2004. 2: 1471-1475.
•  Ram, S.R., Chary, K.P., Salahuddin, S.,Iyengar, D.S. An efficient chemoselective production of amines from azides, using AlCl3/NaBH4.Indian. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 2003. 42B: 935- 937.
•  Reddy, G.S., Salahuddin, S. ,Neelakantan, P., Iyengar, D.S. Conversion of α-arylidene-γ-keto esters to diarylfuran carboxylic acid esters.Heterocyclic Commun.2002. 8: 361-364.